Lijing Si

Virtual single‐cell perturbation and genetic causal inference reveal CSF1R‐dependent immunometabolic communication in iron metabolism‐associated osteoarthritis

Iron dysregulation has emerged as a contributor to osteoarthritis (OA), yet the cell‐communication mechanisms connecting iron‐related genetic signals to joint degeneration remain insufficiently defined. Here, we established an integrative computational framework combining transcriptomic screening, machine learning, Men...