Open access
Aug 2026
Dual regulatory mechanisms of the ZI-LHb circuit in SPS&S model mice: dissociable control of aversion and anxiety through distinct downstream targets.
Post-traumatic stress disorder (PTSD) involves maladaptive aversion processing and anxiety disorders; however, the correlation between these components and their underlying neural circuit mechanisms remains unclear. The single prolonged stress and shock (SPS&S) model reliably induced PTSD-related aversive behaviors in...
Yueqin Liu, Jiahui Qian, Wei Wu et al.
· Molecular Psychiatry · 0 citations