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Liang Zhang

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Aug 2026

The mechanism of SOX4/IGF2BP3/TRIB3 axis inhibiting autophagy and aggravating liver injury in sepsis.

It was found that the SOX4/IGF2BP3/TRIB3 axis was upregulated in septic hepatocytes, and its knockdown alleviated LPS-induced injury and impaired autophagic flux, and this axis exacerbated LPS-induced hepatocyte injury by suppressing autophagic flux.

Wen-Jun Zhao, Jing Zhang, Liang Zhang et al. · 0 citations

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