BACKGROUND
Ischemic white matter injury (WMI) is a core pathological mechanism underlying vascular cognitive impairment, for which effective clinical interventions are currently lacking. The natural flavonoid glycoside Isoschaftoside (ISO) has been reported to exhibit various pharmacological activities, but its effects...
Cheng-Gang Li, Yu-Hao Xu, Huai-Ping Tang et al.· International Immunopharmaco...· 0 citations
Multiple sclerosis (MS) is an incurable and progressive inflammatory disease of the central nervous system (CNS) characterized by inflammatory demyelination, chronic axonal damage, and neurodegeneration. Carabrone (CA), a sesquiterpene lactone from the traditional Chinese herb Carpesium abrotanoides L., demonstrates di...
Huai-Ping Tang, Liang Sun, Bin Jia et al.· European Journal of Pharmaco...· 0 citations
Excessive activation of microglia exacerbates secondary brain injury after ischemic stroke, yet the upstream mechanisms governing this response remain incompletely understood. This study aimed to investigate the role of RIO kinase 3 (RIOK3) in microglia-mediated neuroinflammation after ischemic stroke and to explore th...
Yang Geng, Ningning Zong, Chao Zhou et al.· Experimental Neurology· 0 citations
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