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Liang Cheng

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#protein folding Open access Oct 2026

Synthesis, Preclinical Evaluation, and Clinical Application of the FAPI-Dimer Based on the LARM Platform.

Fibroblast activation protein (FAP) is a promising pan-tumor target for theranostics, but current FAP-targeted radioligands are limited by insufficient tumor retention and suboptimal therapeutic doses. To address these challenges, we developed a novel LARM platform and synthesized the FAPI dimer TH2103-100. The radioch...

Fan Jia, Hui-Hui You, Xin-Ping Li et al. · 0 citations

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