Review
Open access
Sep 2026
Psycho-cardiovascular interaction network in cardiovascular health and disease: signaling pathways and molecular mechanisms
This review synthesizes epidemiologic evidence, summarizes the major mechanisms through which psychological and psychiatric factors may influence cardiovascular function, and focuses on key signaling pathways within the PCIN, including BDNF, PROK/PKR, MAPK, 5-HT/5-HT2A-R, and NLRP3 inflammasome pathways, which may medi...
Ze-Xi Li, Fang-Hui Li, Chun-Yi Yan et al.
· Precision Clinical Medicine · 1 citation