Lian-Hui Zhang

A Hierarchical OhrR–EmrR Regulatory Circuit Fine‐Tunes the Vfm Quorum‐ Sensing System and Virulence in Dickeya oryzae

ABSTRACT Rice foot rot, caused by Dickeya oryzae, is a destructive bacterial disease. The Vfm quorum‐sensing (QS) system is a key virulence regulator of this pathogen. However, the mechanisms by which it perceives and integrates upstream environmental signals for precise transcriptional control are poorly understood. H...

Receptor-like kinase RLK15 binds a fungal RNase effector to enhance autophosphorylation and activate host defense

RdmB Activates the Quorum Quenching Activity of Pseudomonas nitroreducens HS-18 by Direct Regulating Two Sets of DSF Signal Degradation Enzymes.

Findings demonstrated that RdmB and RdmA constitute a potent pair of regulators to modulate DSF metabolism in response to environmental changes and physiological need, which would allow QQ agent HS-18 to activate DSF degradation enzymes when necessary, thus keeping its fitness and competitive edges.

Pseudomonas shiyinii ST4 inhibits sexual mating of Sporisorium scitamineum through the GacS/GacA two-component system and the mib1 gene cluster

ABSTRACT Sugarcane smut is one of the most devastating fungal diseases affecting sugarcane plantations. The virulence of the causative agent, Sporisorium scitamineum, depends on a process called sexual mating of compatible sporidia MAT-1 and MAT-2 to form infectious dikaryotic hyphae. We previously isolated Pseudomonas...

Marine antifouling biocide 4,5-dichloro-2-n-octyl-4-isothiazolin-3-one disrupts sediment microbiome structure and function: insights from absolute quantification and enzyme activity dynamics

Analysis of microbial responses to DCOIT exposure over 30 days demonstrates that DCOIT poses microbial ecological risks beyond toxicity to macroorganisms and should be considered in assessments of antifouling biocides.

Spermidine targets GGA-rich small RNAs for virulence regulation

Summary Spermidine (SPD), a polyamine essential for various biological processes, has long been recognized as a signaling molecule. Yet, its specific molecular targets and mechanisms of action remain elusive. In this study, we uncover a previously unknown mechanism whereby SPD selectively binds to small regulatory RNAs...