Review
Open access
Aug 2026
Timing the origin: chromatin, transcription, and the spatiotemporal control of eukaryotic DNA replication
An updated framework for understanding replication timing as a key layer of genome regulation is provided, with emphasis on chromatin accessibility, histone modifications and variants, transcriptional regulators, and higher-order genome topology.
Anne Soeding, Lia Willerding, Lea Riemann et al.
· Biological chemistry · 0 citations