An integrated genomics–metabolomics pipeline is established that not only expands the structural repertoire of myxobacterial steroids but also provides a blueprint for future discovery of cryptic sterol metabolites and their hidden biological functions.
Bing-Jie Fan, Luo Niu, Teng Liu et al.· Applied and Environmental Mi...· 0 citations
Redox-based chemical warfare is a primary driver of microbial community assembly. Here, we show that the predatory bacterium Myxococcus xanthus employs a spatial division of labor between two inducible monofunctional catalases, mxKatB and mxKatE, to overcome prey-derived hydrogen peroxide (H₂O₂). Quantitative transcrip...
D. Sheng, Xuan-qi Zhang, Xin-yao Yan et al.· bioRxiv· 0 citations
ABSTRACT Peptidylprolyl isomerase (PPIase) catalyzes the rate-limiting step of proline cis-trans isomerization during protein folding. In bacteria, multiple PPIases are commonly present and participate in diverse physiological processes. Myxococcus xanthus DK1622 possesses as many as 17 PPIase genes. We previously repo...
Tian-yu Wan, Rui-You Chen, Zi-Ye Zhou et al.· Applied and Environmental Mi...· 0 citations
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