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Review Open access Sep 2026

Nonlinear association between body roundness index and depressive symptoms in women of reproductive age: The mediating role of systemic inflammation

Among U.S. women of reproductive age, BRI was nonlinearly associated with depressive symptoms, with a significant positive association only above a turning point, and the statistical pattern through WBC is consistent with a hypothesized immune-to-brain pathway linking visceral adiposity to mood.

Li Zhang, Xian-Mei Ma, Gao-Yang Shi et al. · 0 citations

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