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Li-Xing Luo

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Open access Aug 2026

Multi-platform evidence of GSDMD-dependent pyroptosis in malaria with a potential role for TLR7

Background Macrophage-mediated inflammation critically determines malaria pathology. Although pyroptosis contributes to host defense, excessive activation induces severe immunopathology. The precise pyroptotic pathways in splenic macrophages during Plasmodium infection, and the upstream regulatory mechanisms that gover...

Yu-Mei Gong, Yi-Wei Liu, Long-Kun Li et al. · 0 citations

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