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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Li Wang

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Open access Sep 2026

Interplay of neuropeptide Y, metabolic dysfunction, and inflammation in cognitive impairment of major depressive disorder: a sex-stratified study

Major depressive disorder (MDD) is associated with metabolic disturbances (elevated TyG index), peripheral inflammation (IL-6, TNF-α, CRP), and cognitive deficits. Serum NPY levels vary by sex and reproductive aging, influencing appetite changes in MDD. However, the interplay between NPY, metabolic dysfunction, i...

Qian-Fa Yuan, Mohammed A. M. Elhassan, Hong-He Zhang et al. · 0 citations

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