Left ventricular (LV) aneurysm most commonly follows transmural myocardial infarction and is rarely described in dilated cardiomyopathy (DCM). When DCM and ischemic injury coexist, the presentation may be atypical and progression can be rapid.
A 52-year-old man developed chest tightness and dyspnea after an...
Zhi-Hua Yu, Li Yang, Ye Xu et al.· Frontiers in Cardiovascular...· 0 citations
Atherosclerosis (AS) is a chronic inflammatory disorder with substantial global prevalence, wherein macrophage polarization and vascular smooth muscle cells (VSMCs) phenotypic switching are critical pathogenic events. Although G protein-coupled receptor 132 (GPR132) is markedly expressed in macrophages, its specific ro...
Yin Feng, Zheng Cao, Fan Zhang et al.· Inflammation Research· 0 citations
Background Heart failure (HF) after acute myocardial infarction (AMI) remains a major clinical challenge. The triglyceride glucose-waist-to-height ratio (TyG-WHtR) integrates metabolic and obesity indices, yet its prognostic value for AMI-HF is unclear. Methods This retrospective study enrolled 738 AMI patients undergo...
This work used isolated brain vascular fragments to study the blood–brain barrier and applied a combination of deep bulk proteomic analysis, a proteomic ruler approach, and scRNA-seq, assuming a high within-gene correlation between mRNA and protein.
Li-Qun He, Henrik J. Johansson, E. Vázquez-Liébanas et al.· Proceedings of the National...· 0 citations
It is shown that progerin leads to somatic mutation accumulation particularly in VSMCs, highlighting the need for early, cell-type-specific therapeutic intervention in HGPS to prevent permanent vascular tissue damage.
Lara G. Merino, Gwladys Revêchon, Santhilal Subhash et al.· Genome Medicine· 1 citation
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