Liping Wang

Mobile Genetic Elements Driving the Spread of Antimicrobial Resistance in Streptococci

Streptococci are adaptable bacteria that persist as commensals or pathogens under selective pressures. This adaptability is influenced by mobile genetic elements (MGEs), which mediate horizontal gene transfer (HGT) and frequently carry antimicrobial resistance (AMR) and virulence‐associated genes. This review provides...

Phage-ICE tandems facilitate bacterial adaptation and antimicrobial resistance spread

Phages and integrative and conjugative elements (ICEs) drive bacterial evolution, but how their interplay shapes bacterial adaptation and antimicrobial resistance (AMR) dissemination remains unclear. Here, we characterize phage-ICE tandems formed by site-specific accretion of phages and ICEs into cotransferable units....

Intergeneric mobilization of a genomic island mediated by a helper integrative conjugative element from Streptococcus suis to Enterococcus faecalis.

Comparative genomics of the streptococcal mobilome reveals class-specific integration, mobility and antimicrobial resistance cargo

Together, these findings reveal a previously underappreciated class- and host-dependent organization of the streptococcal mobilome and its AMR cargo.