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Li-Ni Huo

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Open access Oct 2026

An Oxidized Mogrol Derivative Alleviates LPS-Induced Acute Lung Injury in Association with Reduced NLRP3 Inflammasome-Associated Inflammatory Responses in Mice

Acute lung injury (ALI) is a severe inflammatory pulmonary disorder with high morbidity and limited treatment options available in clinical settings. Mogrosides, natural products derived from Siraitia grosvenorii, have been shown to exhibit protective effects against ALI, but structural optimization of their aglycone m...

Gui-Ze Feng, Yin-Ting Tuo, Jian Su et al. · 0 citations
Aug 2026

In silico screening of anti-atherosclerotic compounds from Morus alba leaves by machine learning and network pharmacology.

OBJECTIVE This study integrates machine learning with network pharmacology, molecular docking, and molecular dynamics simulations to screen bioactive compounds from Mulberry leaves and elucidate their potential mechanisms against atherosclerosis (AS). METHODS A training dataset of anti-AS active compounds was compile...

Min-Li Gan, Raoqing Liu, Hongsheng Liu et al. · 0 citations

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