Author

Li-Ming Gong

3 papers indexed here

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Aug 2026

Polysaccharide-functionalized metal-polyphenol network-coated porous microspheres for improving the treatment of probiotics in ulcerative colitis.

Probiotic therapy offers a new approach to the treatment of ulcerative colitis (UC), but oral drug delivery still faces challenges such as low gastrointestinal survival rates, insufficient intestinal retention, and poor inflammatory targeting. In this study, a layer-by-layer encapsulation probiotic delivery system (HGM...

Congcong Xiao, Bo-Han Chen, Li-Ming Gong et al. · International journal of pha... · 0 citations

Open access Sep 2026

Thymine-functionalized bPEI nanocomplexes for synergistic STING activation and PD-L1 silencing to potentiate cancer immunotherapy.

Cancer continues to pose a major global health burden. Although immunotherapy has reshaped treatment strategies, its therapeutic effect is frequently limited by a suppressive tumor microenvironment and systemic toxicity. The stimulator of interferon genes (STING) pathway has emerged as a key target for coordinating inn...

Li-Qing Chen, Mong-Hsiu Song, Ming-Ji Jin et al. · Journal of Controlled Releas... · 0 citations

Aug 2026

Self-sustaining ROS-responsive hydrogel enabled delivery of PROTAC/Ce6 nanoparticles via PDT-Epigenetic protein degradation to amplify pyroptosis for enhanced cancer immunotherapy.

Cancer immunotherapy exhibits limited efficacy in immunologically "cold" tumors due to insufficient T-cell infiltration and immunosuppressive tumor microenvironment. The efficacy of photodynamic therapy (PDT) is restricted by inadequate tumor-specific aggregation of photosensitizers and therapeutic resistance regulated...

Li-Ming Gong, Jing Feng, Li-Qing Chen et al. · Biomaterials · 0 citations