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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Li-Li Lu

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Open access Sep 2026

Circulating ANGPTL4 predicts CKD and ESKD risk: insights from large-scale proteomics and senescence mechanisms

The global burden of chronic kidney disease (CKD) is increasing significantly, with aging recognized as a major risk factor associated with accelerated biological aging and poor renal outcomes. Growing evidence links angiopoietin-like protein 4 (ANGPTL4) to both aging and CKD pathogenesis, suggesting its potentia...

Hung-Chen Chang, Rui-Jin Lin, Xu-Chao Gu et al. · 0 citations
Open access Aug 2026

Global ecological associations between overweight/obesity and non-communicable disease prevalence among children aged 5–9 years: a sex-stratified analysis of 174 countries

This study provides epidemiological evidence on robust positive associations between childhood overweight/obesity and a broad spectrum of NCDs, with high prevalence in the Americas/Europe and low in Africa/Southeast Asia.

Wen-Jie Ye, Li Shi, Sha Ye et al. · 0 citations
Open access Jul 2026

Large-Scale Plasma Proteomics Enhances Prediction of Liver-Related Events Among Individuals With Prediabetes and Type 2 Diabetes: A Prospective Cohort Study in the UK Biobank.

The protein risk score demonstrated superior performance compared with the FIB-4 index and the polygenic risk score in predicting incident LREs among individuals with prediabetes and T2D, though external validation in multi-ethnic cohorts is warranted.

Chen-Hao Ye, Zi-Qi Zhang, Yi Ding et al. · 0 citations

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