Discovery and Optimization of AMT‐676, a CDH17‐Targeting ADC for the Treatment of Advanced Gastrointestinal Cancers
ABSTRACT Advanced‐stage gastrointestinal (GI) cancers present an unmet need for innovative therapies, and antibody‐drug conjugates (ADCs) offer promising solutions. This study investigates the antitumor efficacy and toxicity of AMT‐676, a novel ADC targeting Cadherin 17 (CDH17), in GI cancers. Utilizing MabArray screen...