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Li-Hui Wen

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Review Open access Sep 2026

ASF1A: A versatile histone chaperone bridging chromatin dynamics, disease mechanisms and clinical potential (Review)

Anti-silencing function 1A (ASF1A) is an evolutionarily conserved histone H3/H4 chaperone that mediates nucleosome assembly, DNA replication and DNA damage repair. Beyond these canonical biological functions, aberrant ASF1A expression facilitates disease progression by triggering epigenetic dysregulation in multiple ma...

Jun Yin, Xiao-Jian Zhuo, Li-Hui Wen et al. · 0 citations

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