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Open access Oct 2026

PRRSV infection induces mitochondrial damage and releases mitochondrial dsRNA to activate the NLRP3-dependent inflammatory response

Porcine reproductive and respiratory syndrome (PRRS), caused by the PRRS virus (PRRSV), remains one of the most economically significant infectious diseases affecting the global swine industry, resulting in annual losses exceeding US $1.2 billion in the USA alone. PRRSV infects porcine alveolar macrophages (PAMs) and i...

Jiang-Nan Li, Cai-Hong Bi, Li-Guo Gao et al. · 0 citations
Review Open access Sep 2026

The multi-pronged entry of African swine fever virus: from host factors to therapeutic targets

ABSTRACT African swine fever (ASF), caused by the African swine fever virus (ASFV), remains one of the most devastating transboundary animal diseases worldwide, with case fatality rates reaching up to 100% in acute infections. Viral entry represents the first essential step in infection and is an ideal target for the d...

Jia-Qi Li, Chuan-Xia Liu, Wei-Tao Huang et al. · 0 citations

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