Li-Chen Zhang

A guide to cell-type-specific Cre mouse models in atherosclerosis: from background strains to future directions

Atherosclerosis is a chronic vascular inflammatory disease, and mouse models are essential for studying its pathogenesis. The Cre/loxP technology has become the gold standard for cell-type-specific gene targeting. However, the rapid proliferation of Cre driver lines has made model selection increasingly challenging. In...