Author

Li-Chen Chang

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Open access Sep 2026

Vitamin B12 status and long-term fracture risk in a multicenter propensity score–matched cohort

Vitamin B12 status may be associated with fracture risk, but prior evidence is inconsistent, and abnormal concentrations may partly reflect broader nutritional status, comorbidity, or healthcare utilization. We examined whether laboratory-defined vitamin B12 deficiency was associated with subsequent incident fracture...

Chih-Ping Yang, Li-Chen Chang, Yuan-Yuan Pang et al. · Scientific Reports · 0 citations

Open access Aug 2026

COVID-19 and long-term risk of incident laboratory-defined micronutrient deficiency in patients with type 2 diabetes: a multicenter propensity score–matched cohort study

Background COVID-19 has been linked to broad post-acute sequelae, but delayed micronutrient deficiency remains insufficiently characterized. Whether COVID-19 increases long-term risks of laboratory-defined vitamin D, magnesium, and vitamin B12 deficiencies among patients with type 2 diabetes mellitus is unclear. Method...

I.-W. Chen, Li-Chen Chang, Kuo-Chuan Hung · Frontiers in Nutrition · 0 citations

Open access Sep 2026

Long-term risk of incident dementia following documented COVID-19 among older adults with type 2 diabetes: a propensity score-matched cohort study

Background Type 2 diabetes mellitus (T2DM) is a well-established risk factor for dementia, and COVID-19 has been associated with persistent neurological and cognitive sequelae. However, whether this association extends beyond the early post-infection period among older adults with T2DM—a population with compounded vasc...

I.-W. Chen, Li-Chen Chang, C. Ho et al. · Frontiers in Aging Neuroscie... · 0 citations