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Author

Li Chen

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2 papers indexed here

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Open access Oct 2026

Integrating transcriptomic analysis and experimental validation unravels autophagy- and lactylation-related gene signatures in acute myocardial infarction

This integrative study identifies ATM and STAT1 as promising diagnostic biomarkers for AMI, with their expression signatures robustly correlated with both autophagy- and lactylation-associated gene activity scores.

Jun Peng, Li Chen, Li-Zhen Liu et al. · 0 citations
Sep 2026

IRF1-driven chromatin and transcriptional regulation determines the anti-tumor responses to all-trans retinoic acid across cancer types.

All-trans retinoic acid (ATRA) is a potent differentiation inducer successfully used to treat acute promyelocytic leukemia (APL), with its therapeutic efficacy traditionally attributed to targeting the PML/RARα fusion oncoprotein. ATRA also exhibits anti-tumor activity in multiple non-APL malignancies. However, PML/RAR...

W. Jin, Peng Jin, Yun Tan et al. · 0 citations

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