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Lewis E. Kay

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Open access Aug 2026

The dynamic and heterogeneous structure of the non-canonical inflammasome.

The stoichiometry of the non-canonical inflammasome is determined showing that it is heterogeneous, comprised of three major complexes with different numbers of LPS and caspase molecules, and NMR results presented establish that the protease domain of caspase-11 is monomeric in isolation.

Alexander I. M. Sever, James M. Aramini, Jeffrey P. Bonin et al. · 0 citations

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