Open access
Jun 2026
GeoPep: A Geometry-Aware Masked Language Model for Protein-Peptide Binding Site Prediction
GeoPep is introduced, a novel framework for peptide binding site prediction that leverages transfer learning from ESM3, a multimodal protein foundation model that significantly outperforms existing methods in protein–peptide binding site prediction.
Dian Chen, Yunkai Chen, Tong Lin et al.
· Journal of Chemical Informat... · 0 citations