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Author

Leonardo Monrroy

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Open access Aug 2026

XSSDense: Time-resolved X-ray Solution Scattering Density Reconstruction Using a Variational Autoencoder

XSSDense is proposed, a framework that couples a variational autoencoder trained on electron densities from predicted or simulated protein ensembles with a genetic algorithm to refine densities against scattering data and enables structurally grounded electron density reconstructions that intrinsically capture conforma...

Leonardo Monrroy, Sebastian Cardoch, S. Westenhoff · 0 citations

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