Repurposing drugs for multi-target treatment of cytokine storm using machine learning
Background: Cytokine Release Syndrome (CRS) is a major driver of acute organ failure in critical care settings, affecting approximately 49 million people and killing approximately 11 million people annually. Targeting multiple dysregulated feedback loops via single-molecule polypharmacology offers a promising strategy...
Leo Meng, Valentina L. Kouznetsova, Santosh Kesari et al.
· ChemRxiv · 0 citations