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Sponsored Design Multi-Agent AI Systems Using MCP and A2A: Engineer your own Pyt Design Multi-Agent AI Systems Using MCP and A2A: Engineer your own Pyt

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Lennart Evers

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Open access Sep 2026

PPM1H loss alters intrasynaptic alpha-synuclein localization in a LRRK2-dependent manner

Mutations in the LRRK2 gene are a major genetic cause of Parkinson’s disease (PD) and induce hyperphosphorylation of RAB GTPases through increased LRRK2 kinase activity. The phosphatase PPM1H counteracts this activity by selectively dephosphorylating LRRK2-phosphorylated RAB proteins. Here, we used primary PPM1H knocko...

Lennart Evers, Jessica M. Grein, C. A. Boecker · 0 citations

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