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Sep 2026

Concise Generation and Diazo‐Preserving Diversification of β‐Diazoimines

Irradiation of a mixture of vinyldiazo esters and azides with blue light, in the absence of any photocatalyst or additive, generates unconventional β‐diazoimines. Mechanistically, the reaction involves the selective decomposition of vinyldiazo compounds under blue light to form singlet free vinylcarbenes, which und...

Jia-Nan Tian, Yanan Wang, Ming-Qiang Li et al. · 0 citations
Open access Sep 2026

Regioselective Insertion of Diazo Compounds Into 3‐Hydroxyisoindolinones for the Synthesis of Isoquinolones

Both 3‐hydroxyisoindolinones and isoquinolones are structural motifs found in many natural alkaloids, and their derivatives exhibit a wide range of therapeutic applications. Herein, we report the direct conversion of 3‐hydroxyisoindolinones into isoquinolones via a diazo ester insertion reaction. This transformation in...

Yi-Han Gao, Xiao-Fei Chen, Ying-Jie Wang et al. · 0 citations

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