Author

Lei Zheng

2 papers indexed here

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Open access Aug 2026

Orthogonal DNA barcoding enables subpopulation-resolved extracellular vesicle miRNA profiling

Extracellular vesicle–associated microRNAs (EV-miRNAs) hold promise for liquid biopsy, but their clinical utility is hindered by EV heterogeneity. Here, we report DEEPER, a DNA-encoded orthogonal recognition platform for selective barcoding of tumor-derived EV subpopulations and in situ miRNA profiling. DEEPER uses fou...

Ye Zhang, Yi-Tong Zhu, Yu Zhang et al. · Science Advances · 1 citation

Sep 2026

Bio-hybrid Nanostructures Orchestrate Photodynamic Remodeling of the Fusobacterium nucleatum-Associated Colorectal Tumor Niche.

It is demonstrated that the integration of natural bioactivity with supramolecular engineering provides a biocompatible strategy for coordinated tumor-bacterial disruption and immunogenic remodeling of the F. nucleatum-associated tumor niche in CRC.

Maliang Tao, Bin-Bin Wei, Yen-Yu Yang et al. · Advances in Materials · 0 citations