Mesenchymal stem cell-derived extracellular vesicles promote macrophage efferocytosis and inflammation resolution in osteoarthritis through the miR-21a-5p/YAP1 axis
Aim: Osteoarthritis (OA) involves chronic inflammation and cartilage degeneration. Impaired macrophage efferocytosis may contribute to OA progression. This study investigated whether mesenchymal stem cell-derived extracellular vesicles (MSC-EVs) enhance macrophage efferocytosis and inflammation resolution in OA. Metho...