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Aug 2026

Mas receptor activation promotes mitophagy and preserves neuronal function after traumatic brain injury.

Traumatic brain injury (TBI) is a leading global cause of death and long-term disability, primarily due to secondary injury mechanisms such as mitochondrial dysfunction and impaired mitophagy,the selective degradation of damaged mitochondria. While the ACE2/Angiotensin-(1-7)/Mas receptor (MasR) axis is recognized for...

Rui-Li Dang, Lei Wang, Changshui Wang et al. · 0 citations
Open access Sep 2026

Cerebral endothelial cell-derived exosomes target injury sites to rescue cerebral energy crisis after traumatic brain injury

Traumatic brain injury (TBI) triggers a severe cerebral energy crisis causing irreversible neurodegeneration, with no effective targeted therapies available. Traditional TBI research neglects the secretory function of cerebral endothelial cells (CECs), and this study explored whether CEC-derived exosomes (CEC-Exos) e...

Wen-Yuan Zhang, Ling Wang, Tao Zhang et al. · 0 citations

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