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Lei Nie

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Open access Sep 2026

Molecular Cloning, In Silico Characterization, and Promoter Analysis of a Putative ETHE1 Gene from Jatropha curcas

Sulfur metabolism and stress responses are fundamental to plant growth and seed development. ETHE1 encodes a mitochondrial sulfur dioxygenase that plays important roles in these processes; however, its function in Jatropha curcas remains unknown. In this study, we report the cloning and in silico characterization of a...

Mei-Li Zhao, Feng-Jin Han, Lei Nie · 0 citations
Open access Sep 2026

Injectable Self-Healing Fucoidan-Chitosan Hydrogel Incorporating Polydopamine-Silver-Rutin Nanoparticles for Multifunctional Wound Dressing

A multifunctional hydrogel was engineered through the Schiff base reaction between oxidized fucoidan and lysine-modified chitosan for wound dressing with strong antibacterial activity against Escherichia coli and Staphylococcus aureus and exhibited good biocompatibility.

Peng-Xiang Ding, Xin Li, Bin Zhang et al. · 0 citations
Sep 2026

Naringenin/Fe3+ nanoparticles encapsulated into extracellular-mimetic chitosan-based hydrogel as a potential antioxidant and antibacterial wound dressing.

A composite hydrogel was engineered between methionine-grafted chitosan and oxidized quaternized pullulan by Schiff base reaction, exhibiting exceptional antibacterial ability and excellent antioxidant activity, tissue adhesion, self-healing capacity, and tailored rheological properties, confirming that the composite h...

Peng-Xiang Ding, Jing-Yi Li, Xin Li et al. · 0 citations
Open access Sep 2026

Biomedical Hydrogels Based on Oxidized Hyaluronic Acid and Carboxymethyl Chitosan Coordinated with Magnesium Ions

This study presents a biomimetic and easily prepared hydrogel platform that integrates pro-coagulant activity, redox regulation, and on-demand injectability, showing translational potential as bioactive wound covering for bleeding control and oxidative microenvironment regulation.

Lei Nie, Ying-Ying Liang, Yi-Ran Lin et al. · 0 citations
Open access Aug 2026

Schiff Base Hydrogel Bio-Adhesive Using Oxidized Chondroitin Sulfate and Polyethylenimine with Antibacterial Properties and Cytocompatibility

The fabricated hydrogel bio-adhesives exhibited good hemocompatibility, effective intracellular reactive oxygen species (ROS) scavenging activity, favorable cytocompatibility, and promoted cell proliferation.

Lei Nie, Meng-Qing He, Xiao-Ran Hu et al. · 0 citations
Jul 2026

Borate‐Crosslinked Bioadhesives With Double Network Fabricated Using Dopamine‐Conjugated Gelatin and Polyvinyl Alcohol Incorporating Catechin Acid: Potential in Biomedical Applications

Rheological characterization confirmed typical viscoelastic solid behavior, favorable injectability, and excellent self‐healing capability, the latter of which was also supported by macroscopic observations.

Lei Nie, Letian Yan, Yaling Deng et al. · 0 citations
Open access Aug 2026

Biomedical Hydrogel Bio-Adhesive Based on Lactobionic Acid Conjugated Polyethylenimine and Oxidized Dextran with Antioxidant Activity and Cytocompatibility

A facilely fabricated hydrogel bio-adhesive based on lactobionic acid-conjugated polyethylenimine and oxidized dextran via Schiff base linkages yields multifunctional hydrogel bio-adhesives, showing strong promise for wound care and tissue repair applications.

Lei Nie, Xiao-Ran Hu, Shi-Chang Cheng et al. · 1 citation
Open access Jul 2026

Composite Hydrogel Using Methacrylated Silk Fibroin and Mercaptolated Hyaluronic Acid with Encapsulating Zinc-Quercetin Nanozyme

This study provides an experimental basis for developing a new type of wound repair materials that integrate antioxidant, anti-infective, and mechanically adaptive properties, holding significant application potential in oxidative stress-related tissue repair fields.

Lei Nie, Xinran Li, Ru-Qiang Gong et al. · 0 citations
Aug 2026

Fabrication of hybrid photo-crosslinked hydrogels based on mercaptolated chitosan and methacrylated hyaluronic acid via thiol-Michael addition.

Hemolysis assays and cytocompatibility evaluations confirmed the favorable hemocompatibility of the HTP hydrogels, which significantly promoted fibroblast proliferation and migration, indicating their substantial potential for wound healing applications.

Lei Nie, Xin-Ran Li, Meng-Fei Feng et al. · 0 citations

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