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Oct 2026

Methylglyoxal exposure at dietary-relevant concentrations induces cognitive deficits through dopaminergic damage system and metabolic perturbation in zebrafish larvae.

This study investigated the effects of MGO exposure at dietary-relevant concentrations on cognitive function and the underlying mechanisms using zebrafish larvae. Behavioral assessments demonstrated that MGO induced dose-dependent cognitive impairment, with the medium and high dose groups showing a remarkable reduction...

Zhong-Hao Hu, Huang Zhang, Lei Liu et al. · 0 citations
Sep 2026

Honokiol ameliorates pyroptosis in bovine mammary epithelial cells via SIRT3-mediated inhibition of the NLRP3 inflammasome.

Bovine mastitis causes significant economic losses in the dairy industry, with excessive inflammation and pyroptosis in its pathogenesis. Honokiol (HKL), a natural compound that may regulate mitochondrial deacetylase Sirtuin 3 (SIRT3)-related signaling, possesses anti-inflammatory properties. This study aimed to invest...

Shang-D. Tang, Yan-Qiong Wen, Ren-Xin Wu et al. · 0 citations

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