Engineering a compact CgCas12n platform for efficient genome and base editing in mammalian cells.
An enhanced CgCas12n system (eCgCas12n) is established that enables efficient mammalian genome editing and provides an efficient genome- and base-editing platform for functional genetic studies.
Bo-Wen Hou, Xin-Yi Liu, Jia-Wen Fan et al.
· Molecular Systems Biology · 0 citations