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Author

Lei Chen

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2 papers indexed here

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Sep 2026

Bionic 'Trojan Horse' nanoparticles based on Fe-Cu bimetallic MOFs enhance anti-tumor immunotherapy through multimodal synergistic effects.

The therapeutic efficacy of cisplatin-based chemotherapy for lung cancer is often limited by low tumor specificity and off-target toxicity. To address these challenges, we have developed a biomimetic "Trojan horse" nanoparticle (RLMPt-NPs), inspired by the multifunctional properties of biological membranes. The nanopar...

Jie Dai, Jian-Mei Li, Qing-Qing Su et al. · 0 citations
Sep 2026

Spectroscopic insights and theranostic application of a CD44-targeted, GSH/H2S-dual-responsive AIE micellar nanoplatform for targeted tumor imaging and photodynamic therapy.

This study engineered a tumor microenvironment (TME) dual-responsive aggregation-induced emission (AIE) micellar system (HA-SS-TPEDCH-Th) to achieve receptor-guided specific bioimaging and localized photodynamic ablation and highlights the translational promise of actively targeted, dual-locked AIE micelles as a highly...

Lei Chen, Shan-Shan Jiang, Jin-Hui Wang et al. · 0 citations

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