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Author

Lee Wha Gwon

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Open access Aug 2026

Dual-mode application of transcriptional regulation and DNA editing using the ultra-compact TnpB system

A dual-mode genome regulation platform using ISDge10 TnpB effectors and engineered ωRNAs is established, in which modulation of the ωRNA guide length enables switching between programmable transcriptional activation and genome editing.

Yeounsun Oh, Se‑Been Jeon, Lee Wha Gwon et al. · 0 citations

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