Review
Open access
Aug 2026
Epigenetic regulation in medulloblastoma: from tumor heterogeneity to diagnostic, prognostic, and translational applications
Medulloblastoma (MB) is the most common malignant pediatric brain tumor. Epigenetic dysregulation, particularly in Group 3 and Group 4 tumors, is a major driver of tumorigenesis despite relatively few recurrent driver mutations. DNA methylation, histone modification, chromatin remodeling, and non-coding RNAs orchestrat...
Xin-Ling Zhang, Lai-Ling Du, Ke-Wei Tian et al.
· Frontiers in Molecular Neuro... · 0 citations