Open access
Oct 2026
Age-dependent differences in SARS-CoV-2 entry-factor expression and innate immune responses between pediatric and adult liver organoids
Since early 2022, a global surge in cases of severe acute hepatitis of unknown origin (AHUO) in children has been reported, with no definitive aetiology established. Epidemiological evidence suggests a potential link to SARS-CoV-2 infection, particularly during Omicron-predominant periods, yet the mechanisms underl...
Tian-Chen Xue, Jie Hu, Zhe Liu et al.
· Frontiers in Public Health · 0 citations