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Author

Laurent Mely

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Open access Sep 2026

Postprandial ultra-fast insulin versus mealtime fast-acting insulin in adults with cystic fibrosis-related diabetes: A randomized multicentre crossover trial.

AIMS Postprandial administration of ultra-fast-acting insulin (PP-UFI) may offer greater flexibility for individuals with cystic fibrosis-related diabetes (CFRD). This study evaluated whether PP-UFI provides glycaemic control comparable to standard mealtime fast-acting insulin (MT-FI). METHODS Adults with CFRD were e...

Luc Rakotoarisoa, P. Mulette, R. Chiron et al. · 0 citations
Open access Sep 2026

Epigenome-wide association study and functional analyses reveal regulatory loci linked to lung function and diabetes in cystic fibrosis

The findings highlight the biological relevance of epigenetic modifications in cystic fibrosis and support systemic inflammation as a common driver of differential DNA methylation across inflammatory diseases.

Loréna Valdés, Jörg Tost, I. Rivals et al. · 0 citations
Open access Aug 2026

Peripheral muscle dysfunction persists in the era of highly effective CFTR modulators in cystic fibrosis.

Altered muscle performance cannot be explained solely by muscle deconditioning and lower muscle size, suggesting intrinsic muscle alterations, and support the need for comprehensive assessment of peripheral muscle function and the continued prioritisation of interventions aiming to optimise muscle health.

A. Bronstein, Elise Zitta, O. Saidi et al. · 0 citations

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