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Laurence S. Pe

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Review Open access Sep 2026

A hypothesis-driven perspective on GLP-1R-β-catenin pathway crosstalk in astrocyte plasticity and endogenous neural repair.

Astrocytes exhibit pronounced, context-dependent plasticity following central nervous system (CNS) injury; however, their capacity for fate remodeling remains constrained by chromatin architecture, lineage-stabilizing signaling networks, inflammatory and metabolic states, and disease context. Canonical Wnt/β-catenin si...

Sudichhya Tamrakar, Laurence S. Pe, Jiraporn Panmanee et al. · 0 citations

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