Open access
Sep 2026
TALAVE in Breast Cancer: BRCA1/2 Mutation-Dependent Immune Remodeling after PARP Inhibition with Limited Checkpoint Engagement
Only limited benefit of PD-1/PD-L1 blockade in augmenting PARPi activity is suggested and the need for alternative strategies to sustain PARPi-induced immunity is highlighted.
F. Lynce, Kenichi Shimada, Claudine Isaacs et al.
· bioRxiv · 0 citations