Open access
Sep 2026
Neuroinflammatory and Motor Alterations in LRRK2*G2019S Transgenic Mice Without Enhanced Vulnerability to Aging or Chronic MPTP‐Induced Nigrostriatal Neurodegeneration
It is suggested that the G2019S mutation modulates the neuroimmune response but does not exacerbate nigrostriatal neurodegeneration in response to mitochondrial dysfunction, highlighting the mutation's complex role in PD pathophysiology.
Roberto García-Swinburn, Laura Morón-Márquez, Carmen Conde-Naranjo et al.
· Journal of Neurochemistry · 0 citations