Review
Open access
Aug 2026
A comprehensive atlas of somatic mutation rates and mutational signatures in normal human cells
Over the course of a lifetime, somatic mutations accrue in normal human cells, causing variation in cell phenotype and engendering somatic evolution with outcomes ranging from the adaptive immune system to cancer. To inform understanding of somatic evolution in the human body we report the mutation rates and mutational...
M. H. Pham, L. M. R. Harvey, Thomas R. W. Oliver et al.
· bioRxiv · 0 citations