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Author

Laramie E. Duncan

2 papers indexed here

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Open access Sep 2026

Selective depletion of upper-layer somatostatin interneuron subtypes in schizophrenia

Schizophrenia (SCZ) is associated with cortical GABAergic dysfunction, but whether inhibitory interneurons are lost or persist in an altered molecular state remains unresolved. Here, we harmonized seven prefrontal post-mortem single-nucleus RNA-seq datasets onto a fine-grained taxonomy of cortical cell types and meta-a...

Nicole Endresz, M. Fafouti, K. Arbabi et al. · 0 citations
Open access Sep 2026

Specific basal ganglia, amygdala, and cortical neurons are associated with borderline personality disorder (BPD)

Borderline personality disorder (BPD) is clinically significant and poorly understood biologically. We tested which human brain cell types preferentially use genes associated with BPD, implicating two major types of neurons: LAMP5 interneurons and D2 medium spiny neurons. These interrogable cell types provide new avenu...

Hazal Senturk, H. Segal-Gavish, J. Tucciarone et al. · 0 citations

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