Author

Lan-Qing Hu

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Review Sep 2026

Athero-Oncology: Vascular Smooth Muscle Cell Tumor-Like Transformation in Atherosclerosis and Therapeutic Opportunities.

Atherosclerosis (AS) is the main pathological basis of cardiovascular diseases, and its pathogenesis and treatment strategies remain major challenges. Recent advances in single-cell RNA sequencing and lineage tracing have revealed that vascular smooth muscle cells (VSMCs) are not merely passive structural components of...

Xin-Yue Wang, Meng-Na Zhang, Chu-Chuan Meng et al. · Ageing Research Reviews · 0 citations

Open access Aug 2026

Polydatin in combination with hawthorn flavonoids alleviates atherosclerosis by inhibiting mitochondrial division through the YTHDF2-DRP1 axis.

INTRODUCTION The combination of polydatin and hawthorn flavonoids (PH), a traditional Chinese medicine formulation for activating blood circulation and detoxification, has shown the potential to counteract atherosclerosis, but the mechanisms underlying its effects remain unclear. PURPOSE To investigate the protective...

Yu-Juan Li, Xiao-Nan Zhang, Sheng-Jie Yang et al. · Journal of Advanced Research · 1 citation

Aug 2026

Efficient Screening of High Bacterial Cell-Selective Antimicrobial Peptides via Proline Regulation Combined with a Universal Secondary Structure Template.

To study the ″preference″ of bacterial membranes for the secondary structure of antimicrobial peptides (AMPs), we designed a universal palindromic sequence template G(LK)n(KL)nG-NH2 (designated as GnPm, where n = 2-6 and m = 0-3) that can cover various secondary structures of AMPs, with 0 to 3 proline residues uniforml...

Pengyi Yan, Lan-Qing Hu, Bingqian Ren et al. · Journal of Medicinal Chemist... · 0 citations