Aug 2026
PDE4D-CXCL13 axis in gland epithelial cells promotes B cell infiltration in primary Sjögren's syndrome.
It is reported that phosphodiesterase 4D (PDE4D) is markedly up-regulated in glandular epithelial cells from both pSS patients and murine models, correlating tightly with diminished saliva output and heightened B cell infiltration.
Ru-hong Fang, Meiyue Lu, Han-Shuang Liang et al.
· Acta Pharmacologica Sinica · 0 citations