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Author

Lanfeng Zhong

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Preprint Oct 2026

REST: Reliability-Guided Spatial Transcriptomics Supervision for Gene Expression Prediction from Histopathological HE-Stained Images

Histopathology is central to cancer diagnosis, but morphology in Hematoxylin and Eosin (HE)-stained images does not directly reveal the molecular states that characterize disease heterogeneity and inform tumor characterization, prognostic assessment, and biomarker discovery. Spatial Transcriptomics (ST) measures spatia...

Lan-Feng Zhong, Xiang-Yu Sun, Gui-Xuan Xu et al. · 0 citations
Preprint Aug 2026

SUGFW+: An Uncertainty-guided Feature Weighting Framework for Cold Start Active Adaptation of SAM in Medical Image Segmentation

An extended SAM-based Uncertainty-guided Feature Weighting (SUGFW+) framework for CSAL and adaptation of SAM that leverages the SAM for Patch-level Feature and Uncertainty Calculation (PFUC), and introduces a Patch-based Global Distinct Representation (PGDR) module that aggregates patch-level embeddings into highly dis...

Xiaochuan Ma, Ning Zhu, Jia Fu et al. · 1 citation

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