Ladan Jiracek-Sapieha

Hydrogen sulfide as a hypoxia mimetic for improving chronic neural implant integration

This work proposes that hydrogen sulfide (H₂S), an endogenously produced gasotransmitter with cytoprotective, antioxidant, and neuromodulatory functions, can be leveraged as a localized hypoxia mimetic at the neural implant interface to shift the foreign body response toward a more permissive, pro-survival state.