Open access
Jul 2026
TRIM24 stabilizes the p110 CUX1 oncoprotein via USP10 to promote chemoresistance in acute myeloid leukemia.
A novel non-canonical role of TRIM24 as a stabilizer of the p110 CUX1 oncoprotein by recruiting USP10 is revealed, presenting a promising therapeutic target for AML treatment.
Zhiyin Ke, Jie Li, L. Zhong et al.
· Journal of Translational Med... · 0 citations